The curse on the serpent in Genesis 3:14–15 sets the stage for the subsequent course of redemptive history. Obvious New Testament allusions to this passage occur in places such as Luke 10:19; Romans 16:20; and Revelation 12:17. Yet from this point in the book of Genesis, the theme of “enmity between offspring/seed” characterizes the biblical narrative. This passage is ultimately fulfilled in Jesus Christ, the consummate “seed of the woman” who crushes the head of the serpent. In the three curse-speeches given in Genesis 3:14–19, the plotline of history is sketched out.